Current Issue : July-September Volume : 2011 Issue Number : 3 Articles : 4 Articles
The present study was aimed to evaluate analgesic, anti-inflammatory and antipyretic activity of alcoholic and aqueous extract of root of Rotula aquatic L. in mice and rats. The alcoholic extract of R. aquatic L. root at a dose of 200 mg/kg body weight has shown significant analgesic, antipyretic and anti-inflammatory activity as compared to aqueous extract. The result of hot plate method indicated that the total alcoholic extract showed significant increase (P<0.01) in reaction time at a 3, 4 and 6 hours comparable to the reference drug Pentazocin but lesser (P<0.05) after 2 hr. The tail immersion and hot plate tests revealed that plant has high analgesic activity. Both tests showed highest degree of analgesia in alcoholic extract compared to aqueous extract. The total alcoholic extract of R. aquatic L. root at the a dose of 200 mg/kg body weight has shown significant (p<0.01) antipyretic activity as compared to aqueous extract, alcoholic extract also found to have significant result in Carrageenin-induced paw oedema; suspected mode of action may be due to possible inhibition of lipooxygenase pathway....
Previous study reported the presence of anti-inflammatory constituents in Anisomeles indica & Anisomeles malabarica, separately. First time for Anisomeles species, the comparative studies are carried out here for the mentioned activity. The constituents are β- sitosterol (AIC-1), stigmasterol (AMC-1), ovatodiolide (AIE-1 & AME-1), quercetin (AIM-1 & AMM-1) and catechin (AIAc-1 & AMAc-1) isolated from Anisomeles species. The identification of isolated compounds was carried out by various physical, chemical and instrumental techniques. The presence of stigmasterol in A. malabarica differs from the A.indica, which consist β- sitosterol. In-vitro anti-inflammatory models were studied; as inhibition of protein denaturation, effect of membrane stabilization of human RBC. The methanolic herbal extracts of A. malabarica shows strong anti-inflammatory activity at different concentration. The herbal extract showed dose dependent activity, when compare to acetyl salicylic acid and, hydrocortisone as a standard....
Study of Lawsonia inermis L. (Family: Lythraceae) revealed that use of wildlife medicinal resources in a concern not only from the conservation point of view but in the therapeutic point of view. The aerial part of the plant & hairy roots of Lawsonia inermis grown in east African regions mostly. Judgments regarding sufficiency and timing of dose and administration are make more effective the therapy. Lawsonia inermis L. is a much branched glabrous shrub or small tree, cultivated for its leaves although stem bark, roots, flowers and seeds have also been used in traditional medicine. The plant is reported to contain carbohydrates, proteins, flavonoids, tannins and phenolic compounds, alkaloids, terpenoids, quinones, coumarins, xanthones and fatty acids. The plant has been reported to have analgesic, hypoglycemic, hepatoprotective, immunostimulant, anti-inflammatory, antibacterial, antimicrobial, antifungal, antiviral, antiparasitic, antitrypanosomal, antidermatophytic, antioxidant, antifertility, tuberculostatic and anticancer properties. It is now considered as a valuable source of unique natural products for development of medicines against various diseases and also for the development of industrial products. This review gives a bird’s eye view mainly on the pharmacognostic characteristics, traditional uses, phytochemistry and pharmacological actions of the plant....
Pueraria tuberoa DC. (Family- Fabaceae) syn: Vidari & Vidarikanda is generally found in warm and moist regions of India up to 1200 meter elevation, which yet to be fully explored in terms of medicinal plants. It posses anti-microbial, anti-oxidant, nootropic, analgesic, diuretic properties as earlier reported in the literature and hence is an active ingredient of several Ayurvedic formulations like Chyawanprash etc. It is one of the important ‘Rasayana’ drugs mentioned in Ayurveda. Preliminary phamacognostic studies were carried out on the rhizomes including morphological, microscopical, physicochemical studies alongwith phytochemical screening. The protocol followed for elucidating physicochemical properties were as per WHO guidelines. The successive extraction of plant rhizomes was undertaken by using various solvents of increasing polarity and the extracts thus obtained were subjected for phytochemical analysis, followed by thin layer chromatographic examination by optimizing the solvent systems. The phytochemical investigation revealed the presence of glycosides, flavonoids, proteins, amino acids compounds mainly. These preliminary data may be helpful in developing the standardization parameters of Pueraria tuberosa rhizomes....
Loading....